Mauricio Pochettino's Tottenham Hotspur can cement their status as the top dogs in the capital if they end an eight-year wait and defeat Arsenal in the North London derby on Sunday.
Chelsea begin their Premier League title defence against Swansea City on Saturday in the unusual position of heading into a new season having been significantly outspent by their rivals.
Chelsea overpowered West Ham United and Manchester City outclassed West Bromwich Albion as the Premier League title rivals signalled their intent at the start of a hectic holiday programme on Friday.
Andy Carroll scored a eight-minute hat-trick as West Ham United's last London derby at Upton Park ended in a barnstorming 3-3 draw with Arsenal on Saturday -- a result that dented both club's respective ambitions.
Aston Villa were crushed 6-1 by Southampton but joined Leicester City in celebrating Premier League survival on Saturday while Steven Gerrard's farewell party was spoiled as Liverpool lost 3-1 to Crystal Palace.
'I think 70-80 percent of the goals we have conceded are from set pieces. But they are all different and we are still working on it and we defended against Manchester United brilliantly'
Liverpool substitute Adam Lallana struck deep into stoppage time to snatch a 5-4 win over shell-shocked Norwich City in an extraordinary Premier League game at Carrow Road on Saturday.
Liverpool target Chelsea after midweek tinkering, while third-placed Manchester City, whose hopes of qualifying for the Champions League knockout stage were dealt a severe blow in a humiliating 2-1 home defeat by CSKA Moscow on Wednesday, travel south to face struggling Queens Park Rangers.
IMAGES from the English Premier League match played on Saturday
Rediff.com brings you the top highlights of the soccer weekend.
Legendary boxer Muhammad Ali was on Friday buried at Cave Hill Cemetery in his hometown of Louisville, Kentucky.
News of all that's transpired on and off the football field
Frank Lampard could make an emotional appearance against former club Chelsea this weekend as his new employers Manchester City host Jose Mourinho's side in an early showdown between the Premier League's heavyweights. Catch all the action.
Bernardo Silva has made an encouraging start to the Premier League campaign and the Manchester City midfielder said that feeling more settled at his second season with the champions was a key factor in his performances.
Jose Mourinho's side had paid lavish sums to bolster key areas by this time last year but, having claimed the title at a canter, the motto of this transfer window seems to be: if it ain't broke, don't fix it.
Liverpool's Egyptian forward Mohamed Salah scored his 29th Premier League goal six minutes from time to secure a 2-1 win at Crystal Palace that took them up to provisional second spot in the table on Saturday.
Gerrard will wave goodbye to the Liverpool fans in his final home match against Crystal Palace on Saturday.
Stuttering Chelsea retained their Premier League lead by virtue of the alphabet heading into the new year but will need a quick riposte at home to Newcastle United on Saturday (2030 IST) to hold Manchester City at bay.
It was a day of role reversal as Jose Mourinho's often cautious Chelsea thumped Everton 6-3 in a thriller on Saturday while champions Manchester City's attacking talents were blunted in a shock 1-0 home defeat by Stoke City.
Chelsea may have restored some breathing space over Manchester City with a 2-0 win over Newcastle United on Saturday but they have not regained the form that made them runaway title favourites earlier in the season.
The following are talking points from the weekend's Premier League action:
While Chelsea and Manchester City slug it out at the top of the Premier League, Louis van Gaal's Old Trafford revolution gathers ever more momentum in the red half of Manchester.
Zlatan Ibrahimovic was again at his irrepressible best with another double earning Jose Mourinho's increasingly confident Manchester United a 2-0 win at West Bromwich Albion in the Premier League on Saturday.
Flowers from Bangkok in Thailand, Indonesia and Bengaluru, a nizami feast and a rose petal shower await United States President Donald Trump's daughter Ivanka Trump as she heads to Hyderabad on November 28 for the Global Entrepreneurship Summit. The US First Daughter will be accorded the royal treatment at Taj Falaknuma where she will be joining Prime Minister Narendra Modi for dinner on November 28.
City's Aguero doubtful starter for Watford trip
'Our plan is to put the best foot forward for the upcoming tournament and play good matches'
Manchester United football team manager Louis van Gaal has admitted that he might have changed the club's formation too much in his first 11 Premier League games in charge of the Old Trafford outfit, but insists that he retains a 'clear vision' for the team.
News of all that's transpired on and off the football field.
Aston Villa were relegated from the Premier League for the first time since it began in 1992 when they suffered their 24th loss of the season in a 1-0 defeat at Old Trafford on Saturday.
Four wins a row have lifted Manchester United into the Premier League's top four and Louis van Gaal's managerial reign is beginning to bear fruit after a difficult start.
England's Harry Kane and Jamie Vardy struck in a 2-1 friendly win over fellow Euro 2016 finalists Turkey on Sunday as the home side warmed up with a performance that highlighted their potency in attack and defensive limitations.
Leicester go five clear after win at Everton
'If you are a big player, and paid like a big player, you must play like a big player and behave like a big player'
A suspicious package destroyed by a bomb disposal team after prompting the evacuation of Manchester United's stadium on Sunday was a fake device accidentally left behind after a training exercise, police said.
Inter will be his sixth club in a career which began when he made his debut for Anderlecht as a 16-year-old and has taken him to Chelsea, West Bromwich Albion and Everton.
A man who tried to rob Arsenal players Mesut Ozil and Sead Kolasinac at knifepoint in a failed North London carjacking last July was sentenced to 10 years in jail on Friday.
Spain striker Roberto Soldado's penalty on his Premier League debut gave Tottenham Hotspur a 1-0 win at Crystal Palace in their opening match of the season on Sunday.
Chelsea manager Maurizio Sarri made a winning start to life in the Premier League as his team enjoyed a 3-0 win over Huddersfield Town at the John Smith's Stadium on Saturday.